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progressing to extrapyramidal rigidity and tremors ( cogwheel rigidity) of the extremities, uncontrollable grasping and sucking re exes, and coma. Some of their patients showed overt manifestations of nutritional de ciency, such as Wernicke disease, pellagra, scurvy, and polyneuropathy. These authors concluded that the encephalopathy represented an acute form of nicotinic acid de ciency, since most of their patients recovered when treated with a diet of low vitamin B content supplemented by intravenous glucose and saline and large doses of nicotinic acid. Sydenstricker and colleagues (1938) had previously reported the salutary effects of nicotinic acid on the unresponsive state observed in elderly undernourished patients, and Spillane (1947) described a similar syndrome and response to nicotinic acid in the indigent Arab population of the Middle East. The status of this syndrome and its relation to pellagra are uncertain. The clinical, nutritional, and pathologic features were never delineated precisely. Serdaru and associates reported 22 presumed examples of this syndrome in the alcoholic population of the Salpetriere clinic in Paris, all diagnosed retrospectively after ` the nding in postmortem material of pellagra-like changes in nerve cells. Prominent were confusional states, oppositional, paratonic rigidity (gegenhalten), ataxia, and polymyoclonia a picture somewhat like that described by Jolliffe and coworkers (above). Skin lesions were absent. We have not encountered identical cases among the undernourished patients in the alcoholic populations of Boston and Cleveland.

Just as motor pathways descend or come down from both higher and lower motor neurons, sensory pathways ascend or rise up from sensory neurons. A lower or rst-order sensory neuron is a nerve cell that has part of its dendrites modi ed to form sensory receptors. Sensory receptors are specialized nerve endings that are sensitive to a particular kind of goad (poking prod) called a stimulus (STIM-yuh-les). Consider, for example, certain onion-shaped sensory receptors in the skin of the right hand (Figure 14.11). They are sensitive to touch or pressure sensations. A nerve impulse is created, and then it travels over a peripheral nerve, then a spinal nerve, and into the spinal cord. A higher or second-order sensory neuron is then excited. Its axon crosses the body midline to the left side of the spinal cord, and then ascends towards the thalamus (THAL-uhmus). The thalamus is an egg-shaped bedroom (thalam) an oval region nestled deep within the cerebrum. The thalamus is often described as a sensory relay center. This is because sensory nerve impulses (action potentials) are often switched over (or relayed) up onto third-order sensory neurons, whose cell bodies lie within the thalamus. And from the thalamus, the axons of the third-order sensory neurons nally carry the information about the stimulus all the way up to the postcentral gyrus.

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This error can take many forms, including Cannot communicate with printer or There was an error writing to LPT#. This message is typically reported by the OS and indicates that the computer cannot properly communicate with the printer. Start by ensuring that the printer is turned on. If it is not, turn it on, then try to print. You might need to restart the computer to ensure that it redetects the presence of the printer. Next, make sure that the printer cable is firmly and properly attached to both the printer and the computer and that a proper driver has been loaded. If you suspect that the driver is corrupt, remove it, then reload it. Ensure that the printer port has been assigned the proper IRQ and I/O addresses. If this is a parallel port, you will need to check the resources of the port itself. Try the printer in another port or with another computer. Furthermore, look at the printer settings in the OS to ensure that the attached printer matches the type selected in the printer settings area.

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All we are doing here is displaying the line Pick a Pet, and then allowing the user to select one of several animals. (If this were a quiz, the correct answer would of course be cat, as cats are the undisputed masters of the universe.) In the following sections, you ll see what the resultant screens look like on the Nokia and Phone.com micro-browsers.

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